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科学研究

Scientific Research

优秀博士后介绍

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胡雅慧

理学博士  

主管药师

个人简介

2017年于中国药科大学博士毕业后,进入南京医科大学儿童医院药学部工作,于2018年评定为中级职称。本人一直致力于肿瘤及相关疼痛的研究工作。近年以第一作者或通讯作者发表SCI论文7篇,主持国家自然科学基金等各类课题3项。

主持科研项目

1.Gfi-1/MEL-18/HDAC通路在长春新碱诱导的神经病理性疼痛中的作用研究(81803642),国家自然科学基金青年项目,2019.01-2021.12,21.5万

2.PPARγ/Cx43/CXCL1在化疗痛中的作用研究(2019M651903),中国博士后科学基金面上项目,2019.10-2021.09,8万

3.神经保护素D1在儿童化疗痛中作用及其机制研究(2017NJMUZD050),南京医科大学重点项目,2018.01-2020.12,3万

代表性论文

1.Lin Zhou,LuyaoAo, Yunyi Yan, Chengyuan Li, Wanting Li, Anqi Ye,Jihua Liu., Yahui Hu*, Weirong Fang*andYunman Li* (2019) Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression, Neurotherapeutics, 2020,17(1), 340-355.

2.Lin Zhou,LuyaoAo, Yunyi Yan,Wanting Li, Anqi Ye, Yahui Hu*, Weirong Fang*andYunman Li*, The Therapeutic Potential of Chemokines in the Treatment of Chemotherapy- Induced Peripheral Neuropathy, Curr Drug Targets. 2020, 21, 288-301.

3.Yahui Hu, Lin Zhou, Shanshan Wang, Xia Jing, HongliGuo, Fang Sun, YongZhang, FengChen, JingXu* andXing Ji*, Methotrexate Disposition in Pediatric Patients with Acute Lymphoblastic Leukemia: What Have We Learnt from the Genetic Variants of Drug Transporters, Curr Pharm Des.2019, 25, 627-634.

4.YingXiong, Yan Ma, NandaniDarshikaKodithuwakku, Weirong Fang, Lifang Liu,FengwenLif, Yahui Hua*andYunman Li*, Protective effects of Clematichinenoside AR against inflammation and cytotoxicity induced by human tumor necrosis factor-alpha, Int Immunopharmacol. 2019, 75, 105563.

5.Dan Xu#, Nian Xia#, Kai Hou,Fengyang Li, Shijie Chen, Yahui Hu*, Weirong Fang*andYunman Li*,Clematichinenoside Facilitates Recovery of Neurological and Motor Function in Rats after Cerebral Ischemic Injury through Inhibiting Notch/NF-kappaB Pathway, J Stroke Cerebrovasc Dis. 2019; 28, 104288.

6.YujieSu#, Yahui Hu#, Yu Wang#, Xiangting Xu, Yang Yuan, Yunman Li, Zeyuan Wang, Kerong Chen, Fangrong Zhang, Xuefang Ding, Min Li, Jianping Zhou*, Yuan Liu*, Wei Wang*. A precision-guided MWNT mediated reawakening the sunk synergy in RAS for anti-angiogenesis lung cancer therapy. Biomaterials, 2017; 139: 75-90.

7.Yahui Hu, NandaniDarshikaKodithuwakku, Lin Zhou, Chengyuan Li, Dan Han, Weirong Fang, Jihua Liu* and Yunman Li*. L-corydalmine alleviates neuropathic cancer pain induced by tumor compression via CCL2/CCR2 pathway. Molecules 2017; 22(6): 937.


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